Meta-Analysis
Fluconazole is an antifungal medication used for thrush and other fungal or yeast infections. It is available online and offline.
What is Fluconazole
Fluconazole is an antifungal agent that works on soft tissue to treat a wide range of fungal infections. While showing a favourable response to infections of the vagina and urinary tract, the medication comes in especially handy in fungal infections in people having recently undergone organ transplantation.
How does it work
Fluconazole belongs to the class of azole antifungals that work by inhibiting the cytochrome P45O in order to exhibit their therapeutic effects .Lanosterol 14-alpha-demethylase is a C450-dependent enzyme that is present in the cell membrane of fungi and yeasts to help in their growth and multiplication.
Fluconazole targets the lanosterol enzymes and prevents them from producing ergosterol, which is essential for their cellular growth and facilitates their removal from the tissues and impacted regions.
Usage
Fluconazole comes in strengths of 50 mg, 100 mg, and 200 mg in tablets and capsules, with the usage directions depending on your age, severity of thrush, or any other condition for which you are using it.
For example, the dose of the medicine in thrush patients is 150 mg once daily for at least two weeks or till the symptoms get better. In oropharyngeal and oesophagal candidiasis, the strength is increased to 200 mg on the first day, followed by 100 mg till the remaining period of usage.
You can take fluconazole with or without food. Take it with water and avoid alcoholic and caffeinated beverages with it. In case you miss a dose, use it as soon as you remember. Do not overdose on the medicine to make up for the missed dose.
Precautions
- Don’t drive or use heavy machinery after using fluconazole.
- Inform the doctor if you have arrhythmia, liver or kidney problems or a diagnosis of porphyria before starting fluconazole.
- Check with the doctor if you notice a darkening of the skin, unusual tiredness or dizziness after using the drug.
Side-Effects
Despite its safe profile, fluconazole can cause side effects .Some of the common side effects associated with Fluconazole use are nausea, diarrhoea, headache and stomach pain.These are usually reversed by resting and drinking plenty of water.
Rarely, the side effects can increase in intensity, giving rise to hive-like swellings, vomiting and chest tightness.Discontinue the medication if serious side effects arise and get urgent medical attention.
Contraindications and Drug Interactions
The medication is contraindicated in cases of
Individuals allergic or hypersensitive to fluconazole.
In pregnant and breastfeeding women.
In children less than two years old.
In people with serious kidney and liver dysfunction.
The medication can slow down the removal of drugs like Abrocitinib and Flibanserin.
Inform your healthcare provider about your systemic history with any medications that you are on before using fluconazole.
How to buy fluconazole
Fluconazole is a prescription medication. You can buy it in its single-drug or combination version from pharmacies or online medical retailers. Ensure that you use it under the guidance of the physician and use the dose specific to your condition while ordering.
Reviews
There are no reviews yet.